The use of cannabis is associated with a decreased risk of Helicobacter Pylori infection (HPI) – a bacterial stomach infection that can be associated with abdominal pain, weight loss, and ulcers. HPI is relatively common in adults worldwide, though many people with it do not experience severe symptoms. 

A team of investigators from the United States and Canada assessed the relationship between cannabis use and an HPI diagnosis in a nationally representative cohort of 4,556 subjects. 

They reported that subjects with no prior use of cannabis were nearly twice as likely to have HPI as compared to subjects with a history of marijuana use, even after authors adjusted for demographic confounders and comorbidities. 

They concluded: “Recreational cannabis use is associated with diminished risk of HPI. These observations suggest the need for additional research assessing the effects of medical cannabis formulations on HPI.”

Separate studies have shown that cannabis can provide relief to patients with a variety of gastrointestinal disorders, including IBSCrohn’s disease, while preclinical data indicates that cannabinoids can inhibit the development of gastric ulcers. 

Full text of the study, “Relationship between recreational cannabis use and Helicobacter pylori infection,” appears in Cannabis and Cannabinoid Research. Additional information on cannabis and gastrointestinal disorders is available from NORML.

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