Those who consume cannabis and/or cannabis preparations high in the cannabinoid cannabigerol (CBG) say that they are effective therapeutics and that they possess few adverse side-effects, according to data published in the journal Cannabis and Cannabinoid Research.

CBG acid is the parent compound precursor to the more popularized cannabinoids THC and CBD. It is typically only found in minute quantities in harvested cannabis plants. However, in recent years, specially cultivated varieties of the plant possessing higher concentrations of CBG have been reported, particularly in the pacific northwest region of the United States.

A team of researchers affiliated with Washington State University and the University of California at Los Angeles surveyed subjects who self-identified as consumers of CBG-dominant cannabis products.

A majority of survey participants said they used CBG-dominant preparations of cannabis exclusively for medical purposes. Respondents most frequently did so to mitigate symptoms of anxiety, chronic pain, depression, and insomnia.

Most respondents described their symptoms as either “much improved” or “very much improved” following their use of CBG-dominant cannabis, and three-quarters rated it as “superior” to their conventional medications.

Authors concluded: “This is the first patient survey of CBG use to document self-reported efficacy of CBG-predominant cannabis, particularly for anxiety, chronic pain, depression, and insomnia. Most respondents claimed greater efficacy of CBG over conventional pharmacotherapy … and reported a very benign adverse event profile and negligible withdrawal. … This study demonstrates that CBG-predominant cannabis and related products are available and being used by cannabis consumers and demonstrates the urgent need for randomized controlled trials of CBG-predominant cannabis-based medicines to be studied rigorously to assess safety and efficacy as a function of dose, mode of administration, and specific therapeutic indications.”

Full text of the study, “Survey of patients employing cannabigerol-predominant cannabis preparations: Perceived medical effects, adverse events, and withdrawal symptoms,” appears in Cannabis and Cannabinoid Research.

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